What is Genetic Testing and NGS?

Our bodies are composed of tens of trillions of cells, and within each cell is DNA (genes) — a blueprint that records life information, determining our growth, metabolism, health conditions, and even disease risks.

Genetic testing involves analyzing DNA sequences to identify genetic variations that affect health, helping doctors and researchers make more accurate diagnoses, assess risks, and even select the most appropriate treatment methods.

Among these, NGS (Next-Generation Sequencing) is the most advanced genetic testing technology available today. It can analyze a large number of genes at once, providing rapid and accurate genome interpretation. NGS is widely applied in precision oncology, genetic disease diagnosis, and pharmacogenomics (drug response evaluation).

鎧準500癌症基因檢測

Introduction to Galeas CTC

CancerFree Biotech, in collaboration with the UK-based Nonacus Ltd., introduces the Galeas Tumor testing project. Tumor testing project. By combining cutting-edge technology and precision medicine, it offers a new perspective on tumor analysis.

Unlike traditional pathology that uses tissue biopsies, Galeas CTC leverages our proprietary E.V.A. (Ex Vivo Avatar) platform to detect amplified and cultured circulating tumor cells (CTCs), offering three key advantages.

Three Key Advantages

  • More Comprehensive Tumor Information

Traditional tissue biopsies only reflect local tissue conditions, while liquid biopsy cfDNA (circulating free DNA) mainly originates from fragments of dead tumor cells, providing limited information. CancerFree’s culture technology focuses on highly malignant tumor cells, delivering a more complete analysis of tumor behavior.

  • Higher Representativeness and Accuracy

CTCs cultured using the E.V.A. platform accurately reflect the dynamic characteristics of tumors, aiding physicians and patients in making more precise treatment decisions.

  • Non-invasive and Forward-looking

Compared to traditional biopsies, our method reduces invasive burden on patients and opens new possibilities for tumor research and personalized medicine.

E.V.A. Platform
Cultured CTC

E.V.A. Platform
Cultured CTC

Comparison of Different Testing Sample Sources

Sample Source

Mutation Signal

Invasiveness

Limitations

E.V.A. Platform Cultured CTC

Viable tumor cells in blood

強(活性細胞放大)

Low

Cells require cultivation and amplification,
time-consuming

Pathology Biopsy

Tumor tissue

Strong (localized and specific)

High

Sampling restrictions,
not suitable for frequent testing.

cfDNA

DNA from dead cells in blood

Medium (systemic but possibly diluted)

Low

Does not represent active tumors,
limited sensitivity

MKT-CF-NGS頁面_DNA科學家icons-250416-3-010

Suitable Candidates





Cancer patients with recurrence or metastasis
Advanced cancer patients without standard treatment options
Patients unresponsive to standard therapies
Patients with rare or undiagnosed cancers
Patients planning to undergo targeted or immunotherapy post-surgery

Testing Features

519 Genes

Includes Single Nucleotide Variations (SNVs), Copy Number Variations (CNVs), and Insertions/Deletions (INDELs) among the 519 genes

Multiple Cancer Types

Genes include those related to hereditary cancers, pediatric cancer genes, and glioma-associated 1p/19q co-deletion

Immunotherapy

Genes include those related to hereditary cancers, pediatric cancer genes, and glioma-associated 1p/19q co-deletion

Fusion Genes

Includes known fusion mutations: ALK, BRAF, EGFR, FGFR1, FGFR2, FGFR3, NTRK1, NTRK2, NTRK3, RET, ROS1, TMPRSS2

■ Variant Annotation by MH Guide (Molecular Health, Germany). Comprehensive analysis of genetic testing results for clinical reference

■ Data sources includes renowned international journals, ASCO, ESMO, NCCN clinical guidelines, and databases, data updated month

■ Compliance EU IVDR, CAP/CLIA (analytical laboratories), ISO62304, ISO62366, EN 14971, ISO27001, GDPR & HIPAA

IVDR-logo
cap-accreditation-logo
clia-logo

Testing Process

Sample Collection

Circulating tumor cell culture

Gene Extraction and Sequencing

Sequence Analysis and Reporting

Report generation takes approximately six weeks

Common Cancers and Genes

What is Genetic Testing and NGS?

Our bodies are composed of tens of trillions of cells, and within each cell is DNA (genes) — a blueprint that records life information, determining our growth, metabolism, health conditions, and even disease risks.

Genetic testing involves analyzing DNA sequences to identify genetic variations that affect health, helping doctors and researchers make more accurate diagnoses, assess risks, and even select the most appropriate treatment methods.

Among these, NGS (Next-Generation Sequencing) is the most advanced genetic testing technology available today. It can analyze a large number of genes at once, providing rapid and accurate genome interpretation. NGS is widely applied in precision oncology, genetic disease diagnosis, and pharmacogenomics (drug response evaluation).

鎧準500癌症基因檢測

Introduction to Galeas CTC

CancerFree Biotech, in collaboration with the UK-based Nonacus Ltd., introduces the Galeas Tumor testing project. By combining cutting-edge technology and precision medicine, it offers a new perspective on tumor analysis.

Unlike traditional pathology that uses tissue biopsies, Galeas CTC leverages our proprietary E.V.A. (Ex Vivo Avatar) platform to detect amplified and cultured circulating tumor cells (CTCs), offering three key advantages.

鎧準500癌症基因檢測

Galeas CTC簡介

CancerFree Biotech, in collaboration with the UK-based Nonacus Ltd., introduces the Galeas Tumor testing project. Tumor testing project. By combining cutting-edge technology and precision medicine, it offers a new perspective on tumor analysis.

Unlike traditional pathology that uses tissue biopsies, Galeas CTC leverages our proprietary E.V.A. (Ex Vivo Avatar) platform to detect amplified and cultured circulating tumor cells (CTCs), offering three key advantages.

Three Key Advantages

  • More Comprehensive Tumor Information

Traditional tissue biopsies only reflect local tissue conditions, while liquid biopsy cfDNA (circulating free DNA) mainly originates from fragments of dead tumor cells, providing limited information. CancerFree’s culture technology focuses on highly malignant tumor cells, delivering a more complete analysis of tumor behavior.

  • Higher Representativeness and Accuracy

CTCs cultured using the E.V.A. platform accurately reflect the dynamic characteristics of tumors, aiding physicians and patients in making more precise treatment decisions.

  • Non-invasive and proactive

Compared to traditional biopsies, our method reduces invasive burden on patients and opens new possibilities for tumor research and personalized medicine.

Three Key Advantages

  • More Comprehensive Tumor Information

Traditional tissue biopsies only reflect local tissue conditions, while liquid biopsy cfDNA (circulating free DNA) mainly originates from fragments of dead tumor cells, providing limited information. CancerFree’s culture technology focuses on highly malignant tumor cells, delivering a more complete analysis of tumor behavior.

  • Higher Representativeness and Accuracy

CTCs cultured using the E.V.A. platform accurately reflect the dynamic characteristics of tumors, aiding physicians and patients in making more precise treatment decisions.

  • Non-invasive and proactive

Compared to traditional biopsies, our method reduces invasive burden on patients and opens new possibilities for tumor research and personalized medicine.

E.V.A Platform
Cultured CTC

E.V.A Platform
Cultured CTC

Comparison of Different Testing Sample Sources

Sample Source

Mutation Signal

Invasiveness

Limitations

Sample Source

Mutation Signal

Invasiveness

Limitations

Sample Source

Mutation Signal

Invasiveness

Limitations

E.V.A. Platform Cultured CTC

Viable tumor cells in blood

Strong (amplified from active cells)

Low

Cells require cultivation and amplification,
time-consuming

cfDNA

DNA from dead cells in blood

Medium (systemic but possibly diluted)

Low

Does not represent active tumors,
limited sensitivity

Pathology Biopsy

Tumor tissue

Strong (localized and specific)

High

Sampling restrictions,
not suitable for frequent testing.

Comparison of Different Testing Sample Sources

Sample Source

Mutation Signal

Invasiveness

Limitations

Sample Source

Mutation Signal

Invasiveness

Limitations

Limitations

Invasiveness

Mutation Signal

Sample Source

E.V.A.Platform Cultured CTC

Viable tumor cells in blood

Strong (amplified from active cells)

Low

Cells require cultivation and amplification,
time-consuming

cfDNA

DNA from dead cells in blood

Medium (systemic but possibly diluted)

Low

Does not represent active tumors,
limited sensitivity

Pathology Biopsy

Tumor tissue

Strong (localized and specific)

High

Sampling restrictions,
not suitable for frequent testing.

Suitable Candidates





Cancer patients with recurrence or metastasis
Advanced cancer patients without standard treatment options
Patients unresponsive to standard therapies
Patients with rare or undiagnosed cancers
Patients planning to undergo targeted or immunotherapy post-surgery

Suitable Candidates





Cancer patients with recurrence or metastasis
Advanced cancer patients without standard treatment options
Patients unresponsive to standard therapies
Patients with rare or undiagnosed cancers
Patients planning to undergo targeted or immunotherapy post-surgery

Testing Features

519 Genes

Includes Single Nucleotide Variations (SNVs), Copy Number Variations (CNVs), and Insertions/Deletions (INDELs) among the 519 genes

Immunotherapy

Supports immunotherapy, reporting Microsatellite Instability (MSI) and Tumor Mutational Burden (TMB)

Multiple Cancer Types

Genes include those related to hereditary cancers, pediatric cancer genes, and glioma-associated 1p/19q co-deletion

Fusion Genes

Includes known fusion mutations: ALK, BRAF, EGFR, FGFR1, FGFR2, FGFR3, NTRK1, NTRK2, NTRK3, RET, ROS1, TMPRSS2

Testing Features

519 Genes

Includes Single Nucleotide Variations (SNVs), Copy Number Variations (CNVs), and Insertions/Deletions (INDELs) among the 519 genes

Immunotherapy

Supports immunotherapy, reporting Microsatellite Instability (MSI) and Tumor Mutational Burden (TMB)

Multiple Cancer Types

Genes include those related to hereditary cancers, pediatric cancer genes, and glioma-associated 1p/19q co-deletion

Fusion Genes

Includes known fusion mutations: ALK, BRAF, EGFR, FGFR1, FGFR2, FGFR3, NTRK1, NTRK2, NTRK3, RET, ROS1, TMPRSS2

■ Variant Annotation by MH Guide (Molecular Health, Germany). Comprehensive analysis of genetic testing results for clinical reference

■ Data sources includes renowned international journals, ASCO, ESMO, NCCN clinical guidelines, and databases, data updated month

■ Compliance EU IVDR, CAP/CLIA (analytical laboratories), ISO62304, ISO62366, EN 14971, ISO27001, GDPR & HIPAA

■ Variant Annotation by MH Guide (Molecular Health, Germany). Comprehensive analysis of genetic testing results for clinical reference

■ Data sources includes renowned international journals, ASCO, ESMO, NCCN clinical guidelines, and databases, data updated month

■ Compliance EU IVDR, CAP/CLIA (analytical laboratories), ISO62304, ISO62366, EN 14971, ISO27001, GDPR & HIPAA

Testing Process

Sample Collection

Circulating tumor cell culture

Gene Extraction and Sequencing

Sequence Analysis and Reporting

Report generation takes approximately six weeks

Testing Process

Sample Collection

Circulating tumor cell culture

Gene Extraction and Sequencing

Sequence Analysis and Reporting

Report generation takes approximately six weeks

Common Cancers and Genes

Common Cancers and Genes